Ethylene Glycol

Ethylene Glycol

SCHEMBL4854205

C=C(CCC#N)CCC#N.OCCO

nearest known ligand 0.37

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
LOX P28300 1/20 0.30
LOXL3 P58215 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL59407 0.91 ALDH1A1 (0.44) ALDH1A1TDP1LOXLOXL3LOXL2
SCHEMBL11526163 0.81 ALDH1A1 (0.35) ALDH1A1TDP1
SCHEMBL11292505 0.81 TSHR (0.38) ALDH1A1TDP1TSHR
SCHEMBL60363 0.78
SCHEMBL60459 0.74 TSHR (0.41) ALDH1A1TDP1LOXLOXL3LOXL2
SCHEMBL27661739 0.74
SCHEMBL8827997 0.74 TSHR (0.48) ALDH1A1TDP1TSHR
SCHEMBL60457 0.72 TSHR (0.39) ALDH1A1TDP1LOXLOXL3LOXL2
Ethylene Glycol SCHEMBL27678608 0.72
SCHEMBL21348258 0.71 TSHR (0.45) ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7399886-B2 Aminopropylation of alcohols in the presence of amide or ether solvents AIR PRODUCTS AND CHEMICALS, INC. 2008-07-15 US claimed
US-20050054872-A1 Aminopropylation of alcohols in the presence of amide or ether solvents AIR PRODUCTS AND CHEMICALS, INC. 2005-03-10 US claimed
EP-1512675-A1 Aminopropylation of alcohols in the presence of amide or ether solvents AIR PRODUCTS AND CHEMICALS, INC. (US) 2005-03-09 EP claimed
US-4313004-A CATALYTIC HYDROGENATION, BY-PRODUCT INHIBITION MILLIKEN RESEARCH CORPORATION (US) 1982-01-26 US claimed
US-7399886-B2 Aminopropylation of alcohols in the presence of amide or ether solvents AIR PRODUCTS AND CHEMICALS, INC. 2008-07-15 US disclosed
US-20050054872-A1 Aminopropylation of alcohols in the presence of amide or ether solvents AIR PRODUCTS AND CHEMICALS, INC. 2005-03-10 US disclosed
EP-1512675-A1 Aminopropylation of alcohols in the presence of amide or ether solvents AIR PRODUCTS AND CHEMICALS, INC. (US) 2005-03-09 EP disclosed
US-4313004-A CATALYTIC HYDROGENATION, BY-PRODUCT INHIBITION MILLIKEN RESEARCH CORPORATION (US) 1982-01-26 US disclosed