Phenol

Phenol

SCHEMBL4854650

CCCCCCc1ccc(OCCOC)cc1O.Oc1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 14/20 0.60
CNR1 P21554 4/20 0.54
CYP3A4 P08684 2/20 0.54
MAPT P10636 2/20 0.54
MEN1 O00255 1/20 0.54
TP53 P04637 1/20 0.54
ALOX5 P09917 1/20 0.54
TYR P14679 1/20 0.54
ALOX15 P16050 1/20 0.54
TSHR P16473 1/20 0.54
HTT P42858 1/20 0.54
KMT2A Q03164 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
NR5A1 Q13285 1/20 0.49
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5546322 0.94 CNR2 (0.67) CNR2CNR1CYP3A4MAPTMEN1
SCHEMBL4804282 0.90 CNR2 (0.62) CNR2CNR1CYP3A4MAPTMEN1
SCHEMBL4804633 0.90 CNR2 (0.62) CNR2CNR1CYP3A4MAPTMEN1
SCHEMBL4807422 0.90 CNR2 (0.62) CNR2CNR1CYP3A4MAPTMEN1
SCHEMBL9939329 0.81 CNR2 (0.72) CNR2CNR1CYP3A4MAPTMEN1
SCHEMBL30942500 0.80 TYR (0.68) CNR2CNR1CYP3A4MAPTMEN1
SCHEMBL4808524 0.80 MEN1 (0.51) CNR2CNR1CYP3A4MEN1TSHR
SCHEMBL6061474 0.79 CYP3A4 (0.62) CNR2CNR1CYP3A4MAPTMEN1
SCHEMBL4115623 0.79 CNR2 (0.72) CNR2CNR1CYP3A4MAPTMEN1
SCHEMBL4109823 0.79 CNR2 (0.72) CNR2CNR1CYP3A4MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8436083-B2 Multifunctional self-decontaminating surface coating THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2013-05-07 US disclosed
US-20120172489-A1 MULTIFUNCTIONAL SELF-DECONTAMINATING SURFACE COATING THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2012-07-05 US disclosed
US-7452951-B2 Multifunctional self-decontaminating surface coating THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-11-18 US disclosed
US-20080102281-A1 MULTIFUNCTIONAL SELF-DECONTAMINATING SURFACE COATING THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-05-01 US disclosed
US-7339015-B2 Multifunctional self-decontaminating surface coating THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-03-04 US disclosed
US-20070122438-A1 Multifunctional self-decontaminating surface coating THE GOVERNMENT OF THE UNITED STATES, AS RESPRESENTED BY THE SECRETARY OF THE NAVY 2007-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172489-A1 MULTIFUNCTIONAL SELF-DECONTAMINATING SURFACE COATING YWHAZ, EPCAM, LBR CNR2 3930/4885CNR1 3367/4885CYP3A4 3092/4885
US-20070122438-A1 Multifunctional self-decontaminating surface coating YWHAZ, EPCAM, LBR CNR2 3930/4885CNR1 3367/4885CYP3A4 3092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.