⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4847369 | 0.92 | HCAR2 (0.30) | — | |
| SCHEMBL4849678 | 0.85 | LMNA (0.39) | — | |
| SCHEMBL131152 | 0.76 | — | — | |
| SCHEMBL8897521 | 0.76 | TSHR (0.31) | — | |
| SCHEMBL530086 | 0.75 | TSHR (0.42) | — | |
| SCHEMBL11207248 | 0.74 | — | — | |
| SCHEMBL14776899 | 0.73 | TSHR (0.41) | — | |
| SCHEMBL5209514 | 0.72 | MAPT (0.33) | — | |
| SCHEMBL11207271 | 0.72 | — | — | |
| SCHEMBL11614888 | 0.72 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329694-B2 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-02-12 | — | — | US | disclosed |
| EP-1445641-B1 | OCULAR LENS | JOHNSON & JOHNSON VISION CARE (US) | 2007-10-03 | — | — | EP | disclosed |
| US-20040201820-A1 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. | 2004-10-14 | — | — | US | disclosed |
| US-20040198938-A1 | Monomers, polymers and ophthalmic lenses | JOHNSON & JOHNSON VISION CARE, INC. | 2004-10-07 | — | — | US | disclosed |
| EP-1445641-A1 | OCULAR LENS | Johnson & Johnson Vision Care, Inc. (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-1424339-A1 | MONOMERS, POLYMERS AND OPHTHALMIC LENSES | Johson & Johnson Vision Care Inc. (US) | 2004-06-02 | — | — | EP | disclosed |