Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14157786 | 0.85 | MAPT (0.44) | MAPTRAB9APKMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4829746 | 0.84 | MAPT (0.42) | MAPTRAB9APKMMEN1KMT2A | |
| SCHEMBL5155005 | 0.80 | MAPT (0.43) | MAPTRAB9APKMMEN1KMT2A | |
| SCHEMBL4854489 | 0.80 | RAB9A (0.39) | MAPTRAB9APKMMEN1KMT2A | |
| SCHEMBL2028408 | 0.78 | MAPT (0.44) | MAPTRAB9APKMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5426909 | 0.78 | MAPT (0.41) | MAPTRAB9APKMMEN1KMT2A | |
| SCHEMBL7030236 | 0.78 | MAPT (0.41) | MAPTRAB9APKMMEN1KMT2A | |
| SCHEMBL28407954 | 0.76 | MAPT (0.40) | MAPTRAB9APKMMEN1KMT2A | |
| SCHEMBL12696684 | 0.76 | EPHX2 (0.51) | MAPTRAB9AMEN1KMT2APOLB | |
| SCHEMBL14157794 | 0.75 | SMN1; SMN2 (0.44) | MAPTRAB9APKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | claimed |
| US-20060005322-A1 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | claimed |
| EP-1580185-A1 | Secondary n-Alkylhydroxylated p-Phenylendiamins, dye composition for keratin fibers containing them, processes and uses. | L'OREAL (FR) | 2005-09-28 | — | — | EP | claimed |
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-20060005322-A1 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060005322-A1 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | KRT18, CDC73, PRKDC | MAPT 1834/4885RAB9A 3776/4885PKM 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.