Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MPI | P34949 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853674 | 0.85 | MAPT (0.52) | MAPTATMALDH1A1PKMHPGD | |
| Methane SCHEMBL21391655 | 0.82 | ATM (0.50) | MAPTATMALDH1A1PKMHPGD | |
| SCHEMBL4751533 | 0.81 | ATM (0.45) | MAPTATMALDH1A1PKMHPGD | |
| SCHEMBL14673579 | 0.81 | ATM (0.45) | MAPTATMALDH1A1PKMHPGD | |
| SCHEMBL12677688 | 0.81 | ATM (0.45) | MAPTATMALDH1A1PKMHPGD | |
| SCHEMBL19074432 | 0.77 | ALDH1A1 (0.42) | MAPTATMALDH1A1PKMHPGD | |
| SCHEMBL21463 | 0.76 | MAPT (0.41) | MAPTATMALDH1A1PKMHPGD | |
| SCHEMBL15893572 | 0.76 | ATM (0.41) | MAPTATMALDH1A1PKMHPGD | |
| SCHEMBL18403093 | 0.76 | ATM (0.41) | MAPTATMALDH1A1PKMHPGD | |
| SCHEMBL13780434 | 0.76 | ATM (0.41) | MAPTATMALDH1A1PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2023-11-02 | — | — | US | disclosed |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| US-9777024-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2017-10-03 | — | — | US | disclosed |
| EP-2411446-B2 | PROCESS FOR PREPARING UNSATURATED POLYESTER | DSM IP ASSETS BV (NL) | 2017-09-13 | — | — | EP | disclosed |
| US-20160137672-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2016-05-19 | — | — | US | disclosed |
| US-9221843-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150119362-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2015-04-30 | — | — | US | disclosed |
| EP-2411446-B1 | PROCESS FOR PREPARING UNSATURATED POLYESTER | DSM IP ASSETS BV (NL) | 2014-06-25 | — | — | EP | disclosed |
| US-20120101226-A1 | PROCESS FOR PREPARING UNSATURATED POLYESTER | DSM IP ASSETS B.V. (NL) | 2012-04-26 | — | — | US | disclosed |
| EP-2411446-A1 | PROCESS FOR PREPARING UNSATURATED POLYESTER | DSM IP Assets B.V. (NL) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108968-A1 | PROCESS FOR PREPARING UNSATURATED POLYESTER | DSM IP ASSETS B.V. (NL) | 2010-09-30 | — | — | WO | disclosed |
| EP-0445827-B1 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO KK (JP) | 1996-09-25 | — | — | EP | disclosed |
| US-5149834-A | Anticholesterol agent and enzyme inhibitors, for curing arteriosclerosis | FUJIREBIO INC. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445827-A2 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO INC. (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-3935247-A | COBALT OR COPPER PHTHALOCYANINE CATALYST | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119362-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | MAPT 4329/4885ATM 2713/4885ALDH1A1 751/4885 |
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | MAPT 4241/4885ATM 2972/4885ALDH1A1 1152/4885 |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | PDE4A, PDE4B, PDE4C | MAPT 4241/4885ATM 2972/4885ALDH1A1 1152/4885 |
| US-20160137672-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | MAPT 4329/4885ATM 2713/4885ALDH1A1 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.