SCHEMBL4855008

SCHEMBL4855008

c1ccc2cc3c(ccc4cc5c(ccc6c7ccccc7ccc56)cc43)cc2c1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.80
HSD17B10 Q99714 3/20 0.80
CYP1B1 Q16678 2/20 0.80
HIF1A Q16665 1/20 0.80
HPRT1 P00492 4/20 0.70
CYP2A6 P11509 1/20 0.60
TSHR P16473 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
CYP1A2 P05177 4/20 0.57
HPGD P15428 2/20 0.57
ERBB2 P04626 1/20 0.56
FYN P06241 1/20 0.56
MAOA P21397 1/20 0.56
ACHE P22303 1/20 0.56
AHR P35869 1/20 0.56
PAX8 Q06710 1/20 0.50
TRPM4 Q8TD43 1/20 0.50
CYP1A1 P04798 1/20 0.48
MAPT P10636 1/20 0.48
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30954352 1.00 ALDH1A1 (0.80) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL308409 1.00 ALDH1A1 (0.80) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL5470723 1.00 ALDH1A1 (0.80) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
Chrysene SCHEMBL588025 1.00 ALDH1A1 (0.80) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL4847360 1.00 ALDH1A1 (0.80) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL4845538 1.00 ALDH1A1 (0.80) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL4845641 0.98 ALDH1A1 (0.76) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL4855404 0.98 ALDH1A1 (0.76) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL30839397 0.98 ALDH1A1 (0.76) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL1801479 0.98 ALDH1A1 (0.76) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed