SCHEMBL4855703

SCHEMBL4855703

C1=Cc2ccc3c4cccc5cccc(c6ccc1c2c63)c54

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.48
HSD17B10 Q99714 7/20 0.48
HPGD P15428 5/20 0.48
CYP1A2 P05177 4/20 0.48
THRB P10828 1/20 0.48
ERBB2 P04626 1/20 0.43
FYN P06241 1/20 0.43
MAOA P21397 1/20 0.43
ACHE P22303 1/20 0.43
AHR P35869 1/20 0.43
TSHR P16473 7/20 0.39
CYP3A4 P08684 4/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
HPRT1 P00492 1/20 0.35
MAPK1 P28482 2/20 0.34
CASP1 P29466 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4847895 0.94 CYP1A2 (0.44) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL29354688 0.84 ALDH1A1 (0.63) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL29105767 0.84 ALDH1A1 (0.63) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL4848747 0.84 ALDH1A1 (0.63) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL29369890 0.84 ALDH1A1 (0.63) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL347568 0.82 ALDH1A1 (0.60) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL4845055 0.80 CYP1A2 (0.53) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL4501676 0.79 ALDH1A1 (0.63) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL26440 0.79 ALDH1A1 (0.71) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL634848 0.79 ALDH1A1 (0.71) ALDH1A1HSD17B10HPGDCYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240217976-A2 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2024-07-04 US disclosed
US-20230125359-A1 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2023-04-27 US disclosed
US-11560383-B2 Compound and polymer compound containing the compound JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2023-01-24 US disclosed
US-20210002284-A1 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2021-01-07 US disclosed
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-7175922-B2 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY (US) 2007-02-13 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20050106415-A1 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2005-05-19 US disclosed
WO-2005040303-A1 AGGREGATE ORGANIC LIGHT EMITTING DIODE DEVICES EASTMAN KODAK COMPANY (US) 2005-05-06 WO disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11560383-B2 Compound and polymer compound containing the compound RAD51, MDM2, UBE2D3 ALDH1A1 2360/4885HSD17B10 2020/4885HPGD 1942/4885
US-20230125359-A1 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND RAD51, UBE2D3, MDM2 ALDH1A1 2249/4885HSD17B10 1944/4885HPGD 2018/4885
US-20240217976-A2 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND RAD51, MDM2, UBE2D3 ALDH1A1 2389/4885HSD17B10 2041/4885HPGD 1996/4885
US-20210002284-A1 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND RAD51, MDM2, UBE2D3 ALDH1A1 2360/4885HSD17B10 2020/4885HPGD 1942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.