SCHEMBL4855800

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1248947	0.78	PIM1 (0.78)	PIM1PIM2AKR1B1NPC1RAB9A
	SCHEMBL1248944	0.78	PIM1 (0.78)	PIM1PIM2AKR1B1NPC1RAB9A
	SCHEMBL1248930	0.78	GSK3B (0.64)	PIM1PIM2AKR1B1NPC1RAB9A
	SCHEMBL1248928	0.78	GSK3B (0.64)	PIM1PIM2AKR1B1NPC1RAB9A
	SCHEMBL4855804	0.76	PIM1 (0.57)	PIM1PIM2AKR1B1NPC1RAB9A
	SCHEMBL1247705	0.75	PIM1 (1.00)	PIM1PIM2AKR1B1NPC1RAB9A
	SCHEMBL2546911	0.75	PIM1 (1.00)	PIM1PIM2AKR1B1NPC1RAB9A
	SCHEMBL1247708	0.75	PIM1 (1.00)	PIM1PIM2AKR1B1NPC1RAB9A
	SCHEMBL2546776	0.74	PIM1 (0.69)	PIM1PIM2AKR1B1NPC1RAB9A
	SCHEMBL4857392	0.73	PPARG (0.52)	HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.