SCHEMBL4856067

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31230400	0.84	CHRNA7 (0.46)	CHRNA7HTR3AALDH1A1CTNNB1WNT3A
	SCHEMBL843121	0.84	CHRNA7 (0.46)	CHRNA7HTR3AALDH1A1CTNNB1WNT3A
	SCHEMBL1207766	0.83	CHRNA7 (0.48)	CHRNA7HTR3ACTNNB1WNT3ANAMPT
	SCHEMBL844263	0.82	LCK (0.51)	CHRNA7HTR3AALDH1A1KDM4EMEN1
	Lithium Ion SCHEMBL21632921	0.81	CHRNA7 (0.44)	CHRNA7HTR3ACTNNB1WNT3ANAMPT
	Lithium Ion SCHEMBL31230337	0.81	CHRNA7 (0.44)	CHRNA7HTR3ACTNNB1WNT3ANAMPT
	Hydrochloric Acid SCHEMBL27687894	0.81	CHRNA7 (0.47)	CHRNA7HTR3ACTNNB1WNT3ANAMPT
	SCHEMBL659466	0.76	GRM4 (0.40)	CHRNA7HTR3AALDH1A1CTNNB1WNT3A
	SCHEMBL12333124	0.74	TSHR (0.50)	ALDH1A1KDM4EMEN1TP53RAB9A
	SCHEMBL8834576	0.72	CSNK2A2 (0.39)	CHRNA7HTR3ACTNNB1WNT3AGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.