Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16107082 | 0.81 | GSK3B (0.56) | ESR1ESR2GSK3BADKBCHE | |
| SCHEMBL4856554 | 0.80 | ESR1 (0.76) | ESR1ESR2MAPK14PTGS2EGFR | |
| SCHEMBL4853052 | 0.79 | ESR1 (0.51) | ESR1ESR2MAPK14PTGS2 | |
| SCHEMBL17550872 | 0.77 | CA12 (0.51) | — | |
| SCHEMBL25098590 | 0.76 | CA12 (0.54) | — | |
| SCHEMBL6374305 | 0.76 | CA12 (0.54) | — | |
| SCHEMBL12774523 | 0.75 | MCL1 (0.38) | — | |
| SCHEMBL10063913 | 0.75 | MCL1 (0.38) | — | |
| SCHEMBL25628793 | 0.75 | CA12 (0.44) | — | |
| SCHEMBL10063918 | 0.75 | CA12 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388100-B2 | Tertiary amine compounds | NISHIO TETSUYA | 2008-06-17 | — | — | US | disclosed |
| US-20060145145-A1 | Tertiary amine compounds, organic semiconductor devices using the same and organic electroluminescence devices using the same | NISHIO TETSUYA | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060145145-A1 | Tertiary amine compounds, organic semiconductor devices using the same and organic electroluminescence devices using the same | PIEZO1, YES1, SAT1 | ESR1 1360/4885ESR2 3936/4885GSK3B 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.