Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.52 |
| ▸ | PRKCA | P17252 | 5/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GJB2 | P29033 | 1/20 | 0.47 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2198642 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL8144862 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL8145211 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL5425896 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL6290144 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL3875391 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL2198649 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL2297828 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL10325897 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL10326063 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580553-B2 | Phage-associated lytic enzymes for treatment of Bacillus anthracis and related conditions | THE ROCKEFELLER UNIVERSITY (US) | 2013-11-12 | — | — | US | disclosed |
| US-20120164124-A1 | PHAGE-ASSOCIATED LYTIC ENZYMES FOR TREATMENT OF BACILLUS ANTHRACIS AND RELATED CONDITIONS | THE ROCKEFELLER UNIVERSITY | 2012-06-28 | — | — | US | disclosed |
| US-7402309-B2 | Phage-associated lytic enzymes for treatment of Bacillus anthracis and related conditions | THE ROCKEFELLER UNIVERSITY (US) | 2008-07-22 | — | — | US | disclosed |
| EP-1501925-A4 | IDENTIFICATION OF A PHAGE ASSOCIATED LYTIC ENZYME TO RAPIDLY AND SPECIFICALLY DETECT AND KILL BACILLUS ANTHRACIS | NEW HORIZONS DIAGNOSTICS CORP (US) | 2006-10-25 | — | — | EP | disclosed |
| EP-1501925-A2 | IDENTIFICATION OF A PHAGE ASSOCIATED LYTIC ENZYME TO RAPIDLY AND SPECIFICALLY DETECT AND KILL BACILLUS ANTHRACIS | NEW HORIZONS DIAGNOSTICS CORPORATION (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20050004030-A1 | Phage-associated lytic enzymes for treatment of Bacillus anthracis and related conditions | THE ROCKEFELLER UNIVERSITY | 2005-01-06 | — | — | US | disclosed |
| WO-2004027020-A9 | IDENTIFICATION OF A PHAGE ASSOCIATED LYTIC ENZYME TO RAPIDLY AND SPECIFICALLY DETECT AND KILL BACILLUS ANTHRACIS | NEW HORIZONS DIAGNOSTICS CORP (US) | 2004-05-21 | — | — | WO | disclosed |
| WO-2004027020-A2 | IDENTIFICATION OF A PHAGE ASSOCIATED LYTIC ENZYME TO RAPIDLY AND SPECIFICALLY DETECT AND KILL BACILLUS ANTHRACIS | NEW HORIZONS DIAGNOSTICS CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |