SCHEMBL2198642

SCHEMBL2198642

CCCCCCCCCCCCCCCC(=O)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 2/20 0.52
PRKCA P17252 5/20 0.51
AKT1 P31749 1/20 0.50
MAPK1 P28482 1/20 0.50
GJB2 P29033 1/20 0.47
LY96 Q9Y6Y9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8144862 1.00 TLR4 (0.52) TLR4PRKCAAKT1MAPK1GJB2
SCHEMBL8145211 1.00 TLR4 (0.52) TLR4PRKCAAKT1MAPK1GJB2
SCHEMBL4856848 1.00 TLR4 (0.52) TLR4PRKCAAKT1MAPK1GJB2
SCHEMBL5425896 1.00 TLR4 (0.52) TLR4PRKCAAKT1MAPK1GJB2
SCHEMBL6290144 1.00 TLR4 (0.52) TLR4PRKCAAKT1MAPK1GJB2
SCHEMBL3875391 1.00 TLR4 (0.52) TLR4PRKCAAKT1MAPK1GJB2
SCHEMBL2198649 1.00 TLR4 (0.52) TLR4PRKCAAKT1MAPK1GJB2
SCHEMBL2297828 1.00 TLR4 (0.52) TLR4PRKCAAKT1MAPK1GJB2
SCHEMBL10325897 1.00 TLR4 (0.52) TLR4PRKCAAKT1MAPK1GJB2
SCHEMBL10326063 1.00 TLR4 (0.52) TLR4PRKCAAKT1MAPK1GJB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861205-B1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER. OREAL (FR) 2017-12-06 EP claimed
EP-2861205-A1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER, METHOD THEREFOR, AND USE THEREOF L'OREAL (FR) 2015-04-22 EP claimed
CN-104363887-A Compositions, methods and uses comprising pyridine dicarboxylic acid esters and esters of glucose and fatty acids OREAL 2015-02-18 CN claimed
WO-2013186485-A1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER, METHOD THEREFOR, AND USE THEREOF L'OREAL (FR) 2013-12-19 WO claimed
WO-2013117548-A1 COSMETIC COMPOSITION COMPRISING SILICA AEROGEL PARTICLES AND A SUGAR OR A SUGAR DERIVATIVE L'OREAL (FR) 2013-08-15 WO claimed
EP-1837341-B1 Derivative of glucose and vitamin F, compositions containing it, its uses to improve the state of hair OREAL (FR) 2011-08-03 EP claimed
US-7763587-B2 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2010-07-27 US claimed
EP-1837341-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'Oréal (FR) 2007-09-26 EP claimed
EP-1371658-B1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation OREAL (FR) 2007-09-12 EP claimed
US-20070123471-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. 2007-05-31 US claimed
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin L'OREAL (FR) 2006-07-27 US claimed
EP-1551362-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN. L'OREAL (FR) 2005-07-13 EP claimed
WO-2004034958-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN L'OREAL (FR) 2004-04-29 WO claimed
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2004-02-26 US claimed
EP-1371658-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'OREAL (FR) 2003-12-17 EP claimed
US-4614796-A HEMOSTATIC AGENTS, ANTISHOCK AGENTS AND VASCULAR STABILIZATION NIPPON SHINYAKU CO., LTD. (JP) 1986-09-30 US claimed
US-4129649-A Process for producing easily absorbable amorphous steryl glucoside monopalmitates and preparations thereof NIPPON SHINYAKU CO. LTD. (JP) 1978-12-12 US claimed
JP-58074619-A None JP disclosed
EP-0007474-A1 Sterolinhemiesters, process for their preparation and pharmaceutical compositions containing them Roecar Holdings (Netherlands Antilles) N.V. (AN) 1980-02-06 EP disclosed
US-4129649-A Process for producing easily absorbable amorphous steryl glucoside monopalmitates and preparations thereof NIPPON SHINYAKU CO. LTD. (JP) 1978-12-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070123471-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process FASN, ELOVL6, ACSL6 TLR4 2674/4885PRKCA 1803/4885AKT1 3299/4885
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process FASN, ELOVL6, ACSL6 TLR4 2674/4885PRKCA 1803/4885AKT1 3299/4885
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin CUTA, SCD5, SCD TLR4 685/4885PRKCA 979/4885AKT1 3786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.