Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4852683 | 0.95 | HDAC1 (0.43) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4862621 | 0.85 | KMT2A (0.42) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4859235 | 0.80 | CES2 (0.46) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4863430 | 0.78 | MAP2K1 (0.49) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL6295267 | 0.77 | PIM1 (0.46) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL6291248 | 0.76 | NPC1 (0.56) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL6295843 | 0.75 | CES2 (0.44) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4860610 | 0.74 | CES2 (0.40) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4856514 | 0.74 | CES2 (0.40) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4859968 | 0.73 | MAPK1 (0.39) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7411001-B2 | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids | WARNER-LAMBERT COMPANY (US) | 2008-08-12 | — | — | US | disclosed |
| US-20050176820-A1 | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids | WARNER-LAMBERT COMPANY | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176820-A1 | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids | CYP4X1, CYP2A7, CYP4B1 | HDAC1 1778/4885HDAC6 1457/4885HDAC3 903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.