Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860327 | 0.87 | OPRL1 (0.63) | OPRL1OPRM1MEN1KMT2AMTNR1A | |
| SCHEMBL4857749 | 0.84 | OPRL1 (0.55) | OPRL1OPRM1 | |
| SCHEMBL2379029 | 0.83 | OPRL1 (0.67) | OPRL1OPRM1MEN1KMT2AMTNR1A | |
| SCHEMBL4849208 | 0.83 | OPRL1 (0.73) | OPRL1OPRM1MEN1KMT2AMTNR1A | |
| Hydrochloric Acid SCHEMBL302553 | 0.82 | OPRL1 (0.68) | OPRL1OPRM1MEN1KMT2AMTNR1A | |
| Hydrochloric Acid SCHEMBL4853571 | 0.82 | OPRL1 (0.74) | OPRL1OPRM1MEN1KMT2AMTNR1A | |
| SCHEMBL4855428 | 0.82 | OPRL1 (0.66) | OPRL1OPRM1MEN1KMT2AMTNR1A | |
| Hydrochloric Acid SCHEMBL4852102 | 0.81 | OPRL1 (0.67) | OPRL1OPRM1MEN1KMT2AMTNR1A | |
| SCHEMBL4857162 | 0.81 | OPRL1 (0.64) | OPRL1OPRM1MEN1KMT2AMTNR1A | |
| SCHEMBL5343485 | 0.79 | OPRL1 (0.74) | OPRL1OPRM1MEN1KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348354-B2 | Cyclohexylurea compounds | GRUENENTHAL GMBH (DE) | 2008-03-25 | — | — | US | disclosed |
| US-20050261358-A1 | antinociceptive agent of opioid-receptor for treating pain; tert-aminecyclohexyl-urea, or -thiourea, or -amide derivatives; 1-(4-dimethylamino-4-phenylcyclohexyl)-3-(3-phenylpropyl)urea hydrochloride; stereoisomers; racemic mixtures | GRUENENTHAL GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261358-A1 | antinociceptive agent of opioid-receptor for treating pain; tert-aminecyclohexyl-urea, or -thiourea, or -amide derivatives; 1-(4-dimethylamino-4-phenylcyclohexyl)-3-(3-phenylpropyl)urea hydrochloride; stereoisomers; racemic mixtures | OPRL1, OPRM1, OGFRL1 | OPRL1 1/4885OPRM1 2/4885MEN1 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.