Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 16/20 | 0.48 |
| ▸ | BACE2 | Q9Y5Z0 | 5/20 | 0.48 |
| ▸ | CTSD | P07339 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783296 | 0.80 | BACE1 (0.46) | BACE1BACE2CTSDCYP1A2CYP11B1 | |
| SCHEMBL4525852 | 0.79 | BACE1 (0.71) | BACE1BACE2CTSD | |
| SCHEMBL4516614 | 0.74 | BACE1 (0.44) | BACE1BACE2CTSD | |
| SCHEMBL4784977 | 0.73 | BACE1 (0.70) | BACE1BACE2CTSD | |
| Hydrochloric Acid SCHEMBL5137186 | 0.72 | BACE1 (0.38) | BACE1BACE2CTSD | |
| SCHEMBL4536230 | 0.70 | BACE1 (0.69) | BACE1BACE2CTSD | |
| SCHEMBL4524188 | 0.70 | BACE1 (0.66) | BACE1BACE2CTSD | |
| SCHEMBL4783683 | 0.70 | BACE1 (0.77) | BACE1BACE2CTSD | |
| SCHEMBL4532523 | 0.70 | BACE1 (0.68) | BACE1BACE2CTSD | |
| SCHEMBL4783816 | 0.70 | BACE1 (0.68) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | claimed |