Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 6/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4862576 | 1.00 | POLB (0.43) | POLBALDH1A1LMNAGAACNR1 | |
| SCHEMBL4892187 | 0.82 | TAAR1 (0.38) | POLBLMNAMEN1KMT2A | |
| SCHEMBL16888429 | 0.80 | ALDH1A1 (0.56) | POLBALDH1A1LMNAGAACNR1 | |
| SCHEMBL10708947 | 0.80 | POLB (0.43) | POLBALDH1A1LMNAGAACNR1 | |
| Formaldehyde SCHEMBL27526645 | 0.77 | ALDH1A1 (0.53) | POLBALDH1A1LMNAGAACNR1 | |
| Hydrochloric Acid SCHEMBL8926756 | 0.77 | ALDH1A1 (0.41) | POLBALDH1A1LMNAGAACNR1 | |
| SCHEMBL23847917 | 0.76 | CNR1 (0.53) | LMNACNR1CNR2TDP1DAGLA | |
| SCHEMBL180290 | 0.76 | CNR1 (0.53) | LMNACNR1CNR2TDP1DAGLA | |
| SCHEMBL21759190 | 0.76 | CNR1 (0.53) | LMNACNR1CNR2TDP1DAGLA | |
| SCHEMBL20835188 | 0.76 | CNR1 (0.53) | LMNACNR1CNR2TDP1DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312465-A1 | INTERMEDIATE COMPOUNDS IN THE SYNTHESIS OF DRONABINOL | ALPHORA RESEARCH INC. (CA) | 2008-12-18 | — | — | US | claimed |
| US-7323576-B2 | Synthetic route to dronabinol | ALPHORA RESEARCH INC. (CA) | 2008-01-29 | — | — | US | claimed |
| US-20060074252-A1 | Synthetic route to dronabinol | SANDOZ INC. | 2006-04-06 | — | — | US | claimed |
| US-20080312465-A1 | INTERMEDIATE COMPOUNDS IN THE SYNTHESIS OF DRONABINOL | ALPHORA RESEARCH INC. (CA) | 2008-12-18 | — | — | US | disclosed |
| US-7323576-B2 | Synthetic route to dronabinol | ALPHORA RESEARCH INC. (CA) | 2008-01-29 | — | — | US | disclosed |
| US-20060074252-A1 | Synthetic route to dronabinol | SANDOZ INC. | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312465-A1 | INTERMEDIATE COMPOUNDS IN THE SYNTHESIS OF DRONABINOL | CNR1, CNR2, CYP8B1 | POLB 164/4885ALDH1A1 2461/4885LMNA 2589/4885 |
| US-20060074252-A1 | Synthetic route to dronabinol | CNR1, CNR2, CYP8B1 | POLB 304/4885ALDH1A1 2626/4885LMNA 3551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.