SCHEMBL4858488

SCHEMBL4858488

CC1=CC(OC=O)CCC1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4866014 1.00 CYP19A1 (0.37) CYP19A1
SCHEMBL28975120 0.77
SCHEMBL11583404 0.77 CYP19A1 (0.39) CYP19A1
SCHEMBL18461260 0.75
SCHEMBL31564941 0.74 EDNRA (0.32)
SCHEMBL18461259 0.74
SCHEMBL14440888 0.72
SCHEMBL29322980 0.71 AKR1C3 (0.34)
SCHEMBL18458916 0.71
SCHEMBL31564933 0.70 TRPA1 (0.33) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080312465-A1 INTERMEDIATE COMPOUNDS IN THE SYNTHESIS OF DRONABINOL ALPHORA RESEARCH INC. (CA) 2008-12-18 US claimed
US-7323576-B2 Synthetic route to dronabinol ALPHORA RESEARCH INC. (CA) 2008-01-29 US claimed
US-20060074252-A1 Synthetic route to dronabinol SANDOZ INC. 2006-04-06 US claimed
US-20220413385-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING RESIST PATTERN JSR CORPORATION (JP) 2022-12-29 US disclosed
US-20080312465-A1 INTERMEDIATE COMPOUNDS IN THE SYNTHESIS OF DRONABINOL ALPHORA RESEARCH INC. (CA) 2008-12-18 US disclosed
US-7323576-B2 Synthetic route to dronabinol ALPHORA RESEARCH INC. (CA) 2008-01-29 US disclosed
US-20060074252-A1 Synthetic route to dronabinol SANDOZ INC. 2006-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312465-A1 INTERMEDIATE COMPOUNDS IN THE SYNTHESIS OF DRONABINOL CNR1, CNR2, CYP8B1 CYP19A1 1160/4885
US-20060074252-A1 Synthetic route to dronabinol CNR1, CNR2, CYP8B1 CYP19A1 1011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.