⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858604 | 1.00 | — | — | |
| SCHEMBL4858614 | 1.00 | — | — | |
| SCHEMBL108373 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL7431491 | 0.76 | ALOX15 (0.56) | — | |
| SCHEMBL1783669 | 0.75 | KDM1A (0.38) | — | |
| SCHEMBL1783667 | 0.75 | KDM1A (0.38) | — | |
| SCHEMBL22845168 | 0.74 | — | — | |
| SCHEMBL10525110 | 0.74 | — | — | |
| SCHEMBL10525107 | 0.74 | — | — | |
| SCHEMBL574289 | 0.73 | KDM1A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396953-B2 | Angiogenesis inhibitors and pharmaceutical/cosmetic applications thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-07-08 | — | — | US | disclosed |
| US-20070167519-A1 | Novel Angiogenesis inhibitors and pharmaceutical/cosmetic applications thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-07-19 | — | — | US | disclosed |
| EP-1763500-A1 | NOVEL ANGIOGENESIS INHIBITORS AND PHARMACEUTICAL AND COSMETIC USE THEREOF | Galderma Research & Development, S.N.C. (FR) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006010859-A1 | NOVEL ANGIOGENESIS INHIBITORS AND PHARMACEUTICAL AND COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-02-02 | — | — | WO | disclosed |