Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13987276 | 0.99 | ACHE (0.56) | ACHEHTR1ADRD2DRD1HTR2A | |
| Hydrochloric Acid SCHEMBL4861752 | 0.99 | ACHE (0.56) | ACHEHTR1ADRD2DRD1HTR2A | |
| Hydrochloric Acid SCHEMBL4853314 | 0.98 | ACHE (0.55) | ACHEHTR1ADRD2DRD1HTR2A | |
| SCHEMBL13987644 | 0.97 | ACHE (0.58) | ACHE | |
| Hydrochloric Acid SCHEMBL4860641 | 0.96 | ACHE (0.57) | ACHE | |
| SCHEMBL13987304 | 0.96 | ACHE (0.57) | ACHEHTR1ADRD2DRD1HTR2A | |
| SCHEMBL13987306 | 0.95 | ACHE (0.56) | ACHEHTR1ADRD2DRD1HTR2A | |
| Hydrochloric Acid SCHEMBL4860992 | 0.95 | ACHE (0.56) | ACHEHTR1ADRD2DRD1HTR2A | |
| SCHEMBL13987323 | 0.94 | ACHE (0.58) | ACHE | |
| Hydrochloric Acid SCHEMBL4859759 | 0.94 | ACHE (0.55) | ACHEHTR1ADRD2DRD1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | claimed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |