Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488624 | 1.00 | PARP1 (0.46) | PARP1PTGDR2SIGMAR1TMEM97PKM | |
| SCHEMBL5745363 | 0.87 | PARP1 (0.48) | PARP1SIGMAR1TMEM97 | |
| SCHEMBL20703649 | 0.85 | SIGMAR1 (0.50) | PARP1PTGDR2SIGMAR1TMEM97PKM | |
| SCHEMBL3066321 | 0.85 | SIGMAR1 (0.50) | PARP1PTGDR2SIGMAR1TMEM97PKM | |
| SCHEMBL20449106 | 0.83 | PARP1 (0.48) | PARP1PTGDR2SIGMAR1TMEM97 | |
| SCHEMBL2706487 | 0.83 | PARP1 (0.48) | PARP1PTGDR2SIGMAR1TMEM97 | |
| SCHEMBL3068759 | 0.82 | PARP1 (0.48) | PARP1PTGDR2SIGMAR1TMEM97 | |
| SCHEMBL2484442 | 0.81 | TACR1 (0.41) | — | |
| SCHEMBL2484439 | 0.81 | TACR1 (0.41) | — | |
| SCHEMBL2486149 | 0.81 | TACR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390905-B2 | Piperidine compound and process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-24 | — | — | US | disclosed |
| US-20070112029-A1 | Piperidine compound and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
| EP-1693367-A1 | PIPERIDINE COMPOUND AND METHOD FOR PRODUCING SAME | TANABE SEIYAKU CO., LTD. (JP) | 2006-08-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112029-A1 | Piperidine compound and process for preparing the same | NPSR1, TACR1, PRLHR | PARP1 3751/4885PTGDR2 193/4885SIGMAR1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.