SCHEMBL4860008

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5107092	0.91	APP (0.69)	PDE5AAPPMEN1KMT2ALMNA
	SCHEMBL4868370	0.89	PDE5A (0.68)	PDE5AAPPLMNACYP1A2CYP3A4
	SCHEMBL5107785	0.86	PDE5A (0.61)	PDE5AAPPMEN1KMT2ALMNA
	SCHEMBL5104596	0.86	PDE5A (0.55)	PDE5AAPPMEN1KMT2ALMNA
	SCHEMBL4861326	0.86	PDE5A (0.73)	PDE5AAPPMEN1KMT2ALMNA
	SCHEMBL4867367	0.84	PDE5A (0.78)	PDE5AAPPLMNACYP1A2CYP3A4
	SCHEMBL4863948	0.84	APP (0.70)	PDE5AAPPMEN1KMT2ACYP1A2
	SCHEMBL4866297	0.82	CYP1A2 (0.66)	PDE5AMEN1KMT2ALMNACYP1A2
	SCHEMBL4862525	0.82	CYP1A2 (0.55)	PDE5AAPPMEN1KMT2ALMNA
	SCHEMBL4868361	0.80	CYP1A2 (0.64)	PDE5AMEN1KMT2ALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.