Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 2/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486446 | 0.74 | PSEN1 (0.31) | — | |
| SCHEMBL486116 | 0.70 | FFAR1 (0.31) | — | |
| SCHEMBL26388359 | 0.61 | — | — | |
| SCHEMBL8765559 | 0.61 | PTGIR (0.68) | PTGIRSLC9A1 | |
| SCHEMBL16963414 | 0.61 | SLC9A1 (0.36) | SLC9A1 | |
| SCHEMBL27910677 | 0.59 | POLB (0.50) | TOP2ASLC9A1 | |
| SCHEMBL20020325 | 0.59 | POLB (0.42) | TOP2ASLC9A1 | |
| SCHEMBL16862907 | 0.57 | TOP2A (0.42) | TOP2ASLC9A1GRIN2B | |
| SCHEMBL27942309 | 0.57 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL5387962 | 0.57 | SLC9A1 (0.36) | TOP2ASLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411388-A2 | PROCESS FOR THE PRODUCTION OF FUSED, TRICYCLIC SULFONAMIDES | Elan Pharmaceuticals Inc. (US) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010111418-A2 | PROCESS FOR THE PRODUCTION OF FUSED, TRICYCLIC SULFONAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |