⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14217545 | 0.76 | — | — | |
| SCHEMBL4861660 | 0.66 | GAA (0.34) | — | |
| SCHEMBL16520282 | 0.65 | GAA (0.40) | — | |
| SCHEMBL11779069 | 0.48 | — | — | |
| Potassium SCHEMBL31501780 | 0.48 | — | — | |
| SCHEMBL12809719 | 0.42 | TSHR (0.58) | — | |
| SCHEMBL1323076 | 0.36 | — | — | |
| SCHEMBL5517601 | 0.36 | — | — | |
| SCHEMBL1509853 | 0.34 | — | — | |
| Hno SCHEMBL11132997 | 0.33 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355054-B2 | Indole derivatives | NEURIM PHARMACEUTICALS (1991) LTD. (IL) | 2008-04-08 | — | — | US | claimed |
| US-20050159463-A1 | Indole derivatives | NEURIM PHARMACEUTICALS (1991) LTD. (IL) | 2005-07-21 | — | — | US | claimed |
| EP-1189583-B1 | INDOLE DERIVATIVES | NEURIM PHARMA 1991 (IL) | 2005-07-20 | — | — | EP | claimed |
| EP-1189583-A4 | INDOLE DERIVATIVES | NEURIM PHARMA 1991 (IL) | 2004-04-14 | — | — | EP | claimed |
| EP-1189583-A1 | INDOLE DERIVATIVES | NEURIM PHARMACEUTICALS (1991) LIMITED (IL) | 2002-03-27 | — | — | EP | claimed |
| WO-2000072815-A1 | INDOLE DERIVATIVES | NEURIM PHARMACEUTICALS (1991) LTD. (IL) | 2000-12-07 | — | — | WO | claimed |
| US-7355054-B2 | Indole derivatives | NEURIM PHARMACEUTICALS (1991) LTD. (IL) | 2008-04-08 | — | — | US | disclosed |
| US-20050159463-A1 | Indole derivatives | NEURIM PHARMACEUTICALS (1991) LTD. (IL) | 2005-07-21 | — | — | US | disclosed |
| EP-1189583-B1 | INDOLE DERIVATIVES | NEURIM PHARMA 1991 (IL) | 2005-07-20 | — | — | EP | disclosed |
| US-6858642-B1 | Indole derivatives | NEURIM PHARMACEUTICALS (1991) LTD. (IL) | 2005-02-22 | — | — | US | disclosed |
| EP-1189583-A4 | INDOLE DERIVATIVES | NEURIM PHARMA 1991 (IL) | 2004-04-14 | — | — | EP | disclosed |
| EP-1189583-A1 | INDOLE DERIVATIVES | NEURIM PHARMACEUTICALS (1991) LIMITED (IL) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000072815-A1 | INDOLE DERIVATIVES | NEURIM PHARMACEUTICALS (1991) LTD. (IL) | 2000-12-07 | — | — | WO | disclosed |