Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.67 |
| ▸ | WNT3A | P56704 | 3/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.66 |
| ▸ | PDE4A | P27815 | 4/20 | 0.66 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.66 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.66 |
| ▸ | THRA | P10827 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29670763 | 1.00 | CTNNB1 (0.67) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL9375696 | 0.95 | CTNNB1 (0.65) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL9588048 | 0.94 | THRA (0.66) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL31556192 | 0.91 | CTNNB1 (0.73) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL31556194 | 0.90 | CTNNB1 (0.71) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL30313764 | 0.90 | CTNNB1 (0.71) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL6600362 | 0.90 | CTNNB1 (0.71) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL25262527 | 0.88 | PDE4D (0.58) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL10455919 | 0.88 | CTNNB1 (0.83) | CTNNB1WNT3APDE4BTSHRMAPT | |
| SCHEMBL26141260 | 0.87 | KDM4E (0.60) | PDE4DPDE4APDE4BPDE4CCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114737228-B | Circuit board electrotinning brightener and application thereof | 深圳市板明科技股份有限公司 | 2022-08-26 | — | — | CN | claimed |
| CN-114737228-A | Circuit board electrotinning brightener and application thereof | 深圳市板明科技股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-114737228-B | Circuit board electrotinning brightener and application thereof | 深圳市板明科技股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114737228-B | Circuit board electrotinning brightener and application thereof | 深圳市板明科技股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114737228-A | Circuit board electrotinning brightener and application thereof | 深圳市板明科技股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114737228-A | Circuit board electrotinning brightener and application thereof | 深圳市板明科技股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| US-9902710-B2 | Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A) | EXONHIT THERAPEUTICS, SA (FR) | 2018-02-27 | — | — | US | disclosed |
| US-9902710-B2 | Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A) | EXONHIT THERAPEUTICS, SA (FR) | 2018-02-27 | — | — | US | disclosed |
| US-9902710-B2 | Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A) | EXONHIT THERAPEUTICS, SA (FR) | 2018-02-27 | — | — | US | disclosed |
| US-20170158606-A1 | FLUORINE-CONTAINING COMPOUND, SUBSTRATE FOR PATTERN FORMATION, PHOTODEGRADABLE COUPLING AGENT, PATTERN FORMATION METHOD, AND COMPOUND | KANAGAWA UNIVERSITY (JP) | 2017-06-08 | — | — | US | disclosed |
| US-9606437-B2 | Fluorine-containing compound, substrate for pattern formation, photodegradable coupling agent, pattern formation method, and compound | KANAGAWA UNIVERSITY (JP) | 2017-03-28 | — | — | US | disclosed |
| US-6844359-B2 | Substituted imides | CELGENE CORPORATION (US) | 2005-01-18 | — | — | US | disclosed |
| US-20020143027-A1 | Novel substituted imides | MULLER GEORGE W (US) | 2002-10-03 | — | — | US | disclosed |
| US-6429221-B1 | INHIBITORS OF TUMOR NECROSIS FACTOR; USED TO TREAT CACHEXIA, ENDOTOXIC SHOCK, AND RETROVIRUS REPLICATION | CELGENE CORPORATION | 2002-08-06 | — | — | US | disclosed |
| EP-0800514-A1 | SUBSTITUTED IMIDES AS TNF INHIBITORS | CELGENE CORPORATION (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020926-A9 | SUBSTITUTED IMIDES AS TNF INHIBITORS | — | 1996-09-26 | — | — | WO | disclosed |
| WO-1996020926-A1 | SUBSTITUTED IMIDES AS TNF INHIBITORS | CELGENE CORPORATION (US) | 1996-07-11 | — | — | WO | disclosed |
| US-4757084-A | Pharmaceuticals | MERCK & CO., INC. (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0217204-A1 | Trans-2-(3,4,5-trimethoxyphenyl)-5-(5,6-dimethoxy-3-pyridyl)-tetrahydrothiophene, a PAF-antagonist | MERCK & CO. INC. (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0154887-A1 | New 2,5-diaryl tetrahydrothiophenes and analogs thereof as paf-antagonists | MERCK & CO. INC. (US) | 1985-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143027-A1 | Novel substituted imides | TNF, MIF, TNFRSF1A | CTNNB1 3154/4885WNT3A 4135/4885PDE4D 4166/4885 |
| US-20170158606-A1 | FLUORINE-CONTAINING COMPOUND, SUBSTRATE FOR PATTERN FORMATION, PHOTODEGRADABLE COUPLING AGENT, PATTERN FORMATION METHOD, AND COMPOUND | AFF1, AFF2, AFF4 | CTNNB1 2620/4885WNT3A 2057/4885PDE4D 4160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.