Octane

Octane

SCHEMBL4861483

CCCCCCCC.c1ccc2c(c1)CCC2

nearest known ligand 0.55

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.55
ALDH1A1 P00352 2/20 0.52
CYP2D6 P10635 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49
SIGMAR1 Q99720 9/20 0.47
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
EBP Q15125 1/20 0.42
NAMPT P43490 2/20 0.42
GPR84 Q9NQS5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptane SCHEMBL9302529 0.95 TSHR (0.62) TSHRALDH1A1CYP2D6CYP1A2CYP2C19
Undecane SCHEMBL8468032 0.95 TSHR (0.62) TSHRALDH1A1CYP2D6CYP1A2CYP2C19
Hexane SCHEMBL11580856 0.93 TSHR (0.65) TSHRALDH1A1CYP2D6CYP1A2CYP2C19
Butane SCHEMBL2150151 0.87 TSHR (0.63) TSHRALDH1A1SIGMAR1MEN1KMT2A
SCHEMBL28860753 0.87 DNM1 (0.46) TSHRALDH1A1CYP2D6CYP1A2CYP2C19
Butane SCHEMBL8909318 0.82 TSHR (0.72) TSHRALDH1A1LMNASIGMAR1MEN1
Hexanoate SCHEMBL9453801 0.81 AKR1B1 (0.55) TSHRALDH1A1LMNAGAAMEN1
Propylamine SCHEMBL6559405 0.81 TSHR (0.55) TSHRALDH1A1SIGMAR1MEN1KMT2A
Alcohol SCHEMBL1872106 0.80 TSHR (0.60) TSHRALDH1A1MEN1KMT2A
SCHEMBL1901557 0.80 CYP1A2 (0.50) TSHRALDH1A1CYP2D6CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7446193-B2 Methods for detection of chloral hydrate in dichloroacetic acid ISIS PHARMACEUTICALS, INC. (US) 2008-11-04 US claimed
CN-102896324-A Process for producing silver nanoparticles XEROX CORP 2013-01-30 CN disclosed