Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.59 |
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | CRHBP | P24387 | 4/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4861171 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2AMEN1CRHBP | |
| SCHEMBL14003609 | 0.99 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2AMEN1CRHBP | |
| SCHEMBL14003611 | 0.94 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2AMEN1CRHBP | |
| SCHEMBL4951801 | 0.93 | MAPT (0.62) | ALDH1A1MAPTKMT2AMEN1CRHBP | |
| SCHEMBL4952994 | 0.93 | MAPT (0.62) | ALDH1A1MAPTKMT2AMEN1CRHBP | |
| SCHEMBL9682978 | 0.88 | KMT2A (0.65) | ALDH1A1MAPTKMT2AMEN1CRHBP | |
| SCHEMBL4954687 | 0.88 | MAPT (0.64) | ALDH1A1MAPTKMT2AMEN1CRHBP | |
| SCHEMBL9098100 | 0.87 | MAPT (0.57) | ALDH1A1MAPTKMT2AMEN1CRHBP | |
| SCHEMBL14364287 | 0.84 | MAPT (0.60) | ALDH1A1MAPTKMT2AKAT2BPOLB | |
| SCHEMBL4862815 | 0.83 | KMT2A (0.56) | ALDH1A1MAPTKMT2AMEN1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | disclosed |
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | disclosed |
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | disclosed |
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | disclosed |
| EP-1568355-A1 | N-alkylhydroxilated secondary paraphenylenediamine which is ortho- and/or meta substituted, composition for dying keratinous fibres comprising this paraphenylenediamine, methods based on this composition and uses. | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | KRT18, CDC73, TYR | ALDH1A1 968/4885MAPT 744/4885KMT2A 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.