Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | SLC22A2 | O15244 | 3/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.57 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.57 |
| ▸ | PLAU | P00749 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | NOS1 | P29475 | 6/20 | 0.55 |
| ▸ | NOS3 | P29474 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136574 | 0.85 | KMT2A (1.00) | MEN1KMT2ASLC22A2SLC22A1SLC22A3 | |
| SCHEMBL139363 | 0.85 | KMT2A (1.00) | MEN1KMT2ASLC22A2SLC22A1SLC22A3 | |
| SCHEMBL24662980 | 0.85 | KMT2A (1.00) | MEN1KMT2ASLC22A2SLC22A1SLC22A3 | |
| Hydrochloric Acid SCHEMBL28549744 | 0.83 | KMT2A (0.95) | MEN1KMT2ASLC22A2SLC22A1SLC22A3 | |
| Hydrochloric Acid SCHEMBL9773794 | 0.83 | KMT2A (0.95) | MEN1KMT2ASLC22A2SLC22A1SLC22A3 | |
| SCHEMBL6967013 | 0.82 | MEN1 (0.76) | MEN1KMT2ASLC22A2SLC22A1SLC22A3 | |
| SCHEMBL4854784 | 0.81 | SLC22A2 (0.53) | MEN1KMT2ASLC22A2SLC22A1SLC22A3 | |
| SCHEMBL8328537 | 0.80 | MEN1 (0.73) | MEN1KMT2ASLC22A2SLC22A1SLC22A3 | |
| Hydrochloric Acid SCHEMBL7560014 | 0.80 | MEN1 (0.73) | MEN1KMT2ASLC22A2SLC22A1SLC22A3 | |
| SCHEMBL11789365 | 0.80 | CYP2D6 (0.85) | MEN1KMT2ASLC22A2SLC22A1SLC22A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365069-B2 | Pyrimidone derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365069-B2 | Pyrimidone derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365069-B2 | Pyrimidone derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-20040259891-A1 | Novel pyrimidon derivatives | ORCHID CHEMICAL & PHARMACEUTICALS LIMITED (IN) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259891-A1 | Novel pyrimidon derivatives | TYMS, TPMT, TYMP | MEN1 917/4885KMT2A 4298/4885SLC22A2 1157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.