Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NOS1 | P29475 | 5/20 | 0.52 |
| ▸ | NOS3 | P29474 | 3/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6967345 | 0.98 | MEN1 (0.73) | MEN1KMT2ACYP2D6HIF1AMAPT | |
| SCHEMBL139363 | 0.87 | KMT2A (1.00) | MEN1KMT2ACYP2D6HIF1AMAPT | |
| SCHEMBL24662980 | 0.87 | KMT2A (1.00) | MEN1KMT2ACYP2D6HIF1AMAPT | |
| SCHEMBL24136574 | 0.87 | KMT2A (1.00) | MEN1KMT2ACYP2D6HIF1AMAPT | |
| Hydrochloric Acid SCHEMBL28549744 | 0.85 | KMT2A (0.95) | MEN1KMT2ACYP2D6HIF1AMAPT | |
| Hydrochloric Acid SCHEMBL9773794 | 0.85 | KMT2A (0.95) | MEN1KMT2ACYP2D6HIF1AMAPT | |
| SCHEMBL8328537 | 0.82 | MEN1 (0.73) | MEN1KMT2ACYP2D6HIF1AMAPT | |
| Hydrochloric Acid SCHEMBL7560014 | 0.82 | MEN1 (0.73) | MEN1KMT2ACYP2D6HIF1APOLB | |
| SCHEMBL11789365 | 0.82 | CYP2D6 (0.85) | MEN1KMT2ACYP2D6HIF1AMAPT | |
| SCHEMBL28859630 | 0.82 | MEN1 (0.73) | MEN1KMT2ACYP2D6HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713483-B1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRAZENECA AB (SE) | 2003-01-15 | — | — | EP | disclosed |
| US-6030985-A | Amidine derivatives with nitric oxide synthetase activities | ASTRA AKTIEBOLAG (SE) | 2000-02-29 | — | — | US | disclosed |
| US-5807885-A | Amidine derivatives with nitric oxide synthetase activities | ASTRA AKTIEBOLAG (SE) | 1998-09-15 | — | — | US | disclosed |
| WO-1995005363-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRA AKTIEBOLAG (SE) | 1995-02-23 | — | — | WO | disclosed |