Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 19/20 | 0.69 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025994 | 0.89 | APP (0.60) | APPMAPTSNCA | |
| SCHEMBL4925188 | 0.85 | APP (0.71) | APPMAPTSNCA | |
| SCHEMBL4925178 | 0.85 | APP (0.71) | APPMAPTSNCA | |
| SCHEMBL14026011 | 0.83 | APP (0.66) | APPTUBB1MAPT | |
| SCHEMBL2374207 | 0.82 | APP (1.00) | APPMAPTSNCA | |
| SCHEMBL2374221 | 0.82 | APP (1.00) | APPMAPTSNCA | |
| SCHEMBL14026004 | 0.81 | APP (0.69) | APPTUBB1MAPT | |
| SCHEMBL13420098 | 0.78 | APP (0.67) | APP | |
| SCHEMBL12973266 | 0.78 | APP (0.68) | APPMAPTSNCA | |
| SCHEMBL4746463 | 0.77 | APP (0.60) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008128129-A1 | HALO-STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING OF AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-10-23 | — | — | WO | disclosed |