Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 20/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | SNCA | P37840 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4925188 | 1.00 | APP (0.71) | APPMAPTSNCA | |
| SCHEMBL14025994 | 0.92 | APP (0.60) | APPMAPTSNCA | |
| SCHEMBL4862377 | 0.85 | APP (0.69) | APPMAPTSNCA | |
| SCHEMBL2373466 | 0.83 | APP (1.00) | APPMAPTSNCA | |
| SCHEMBL2373474 | 0.83 | APP (1.00) | APPMAPTSNCA | |
| SCHEMBL4749268 | 0.81 | APP (0.71) | APPMAPTSNCA | |
| SCHEMBL2832329 | 0.80 | APP (1.00) | APPMAPTSNCA | |
| SCHEMBL2836082 | 0.80 | APP (1.00) | APPMAPTSNCA | |
| Florbetaben SCHEMBL12641432 | 0.80 | APP (1.00) | APPMAPTSNCA | |
| SCHEMBL2835377 | 0.80 | APP (1.00) | APPMAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080253967-A1 | Halo-Stilbene Derivatives And Their Use For Binding And Imaging Of Amyloid Plaques | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080253967-A1 | Halo-Stilbene Derivatives And Their Use For Binding And Imaging Of Amyloid Plaques | APP, APBA1, HSPBP1 | APP 1/4885MAPT 6/4885SNCA 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.