SCHEMBL486245

SCHEMBL486245

O=c1c2ccccc2n(CC=Cc2ccccc2)c2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.53
P2RX4 Q99571 5/20 0.53
ALDH1A1 P00352 2/20 0.51
GLA P06280 1/20 0.51
LMNA P02545 1/20 0.48
DHFR P00374 1/20 0.45
TSHR P16473 1/20 0.45
ALDH3A1 P30838 1/20 0.44
RCE1 Q9Y256 1/20 0.44
PAM P19021 1/20 0.41
KDM4E B2RXH2 2/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29811275 0.81 NPSR1 (0.49) NPSR1P2RX4ALDH1A1LMNATSHR
SCHEMBL27210133 0.81 NPSR1 (0.49) NPSR1P2RX4ALDH1A1LMNATSHR
SCHEMBL12668379 0.78 ALDH1A1 (0.51) NPSR1ALDH1A1LMNATSHRALDH3A1
SCHEMBL11011183 0.78 ALDH1A1 (0.51) NPSR1ALDH1A1LMNATSHRALDH3A1
SCHEMBL13607472 0.77 ALDH1A1 (0.60) P2RX4ALDH1A1GLADHFRRCE1
SCHEMBL30493502 0.75 ALDH1A1 (0.58) P2RX4ALDH1A1GLALMNADHFR
SCHEMBL9709253 0.75 ALDH1A1 (0.58) P2RX4ALDH1A1GLALMNADHFR
SCHEMBL16066062 0.74 NPSR1 (0.45) NPSR1TSHRMAPK1
SCHEMBL16066061 0.74 NPSR1 (0.45) NPSR1TSHRMAPK1
SCHEMBL11632469 0.71 ALDH1A1 (0.45) NPSR1ALDH1A1LMNATSHRALDH3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8912248-B2 Pigment dispersion and ink composition, curable composition and curable ink composition making use of the same FUJIFILM CORPORATION (JP) 2014-12-16 US disclosed
US-8293837-B2 Pigment dispersion, and ink composition, curable composition and curable ink composition produced with pigment dispersion FUJIFILM CORPORATION (JP) 2012-10-23 US disclosed
EP-2233536-B1 Pigment dispersion and ink composition, curable composition and curable ink composition making use of the same FUJIFILM CORP (JP) 2012-05-16 EP disclosed
EP-2233537-B1 Pigment dispersion, and ink composition, curable composition and curable ink composition produced with pigment dispersion FUJIFILM CORP (JP) 2012-02-01 EP disclosed
EP-2233537-A1 Pigment dispersion, and ink composition, curable composition and curable ink composition produced with pigment dispersion Fujifilm Corporation (JP) 2010-09-29 EP disclosed
EP-2233536-A1 Pigment dispersion and ink composition, curable composition and curable ink composition making use of the same Fujifilm Corporation (JP) 2010-09-29 EP disclosed
US-20100240825-A1 PIGMENT DISPERSION, AND INK COMPOSITION, CURABLE COMPOSITION AND CURABLE INK COMPOSITION PRODUCED WITH PIGMENT DISPERSION FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed
US-20100240830-A1 PIGMENT DISPERSION AND INK COMPOSITION, CURABLE COMPOSITION AND CURABLE INK COMPOSITION MAKING USE OF THE SAME FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed