SCHEMBL4862636

SCHEMBL4862636

CCC(=O)NC[C@H]1CN(c2cccc(F)c2N2CCC(OS(C)(=O)=O)CC2)C(=O)O1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.41
MAOA P21397 3/20 0.41
LMNA P02545 1/20 0.41
PTGS1 P23219 1/20 0.41
CALML3 P27482 1/20 0.41
SDHA P31040 1/20 0.41
F10 P00742 6/20 0.40
GRM2 Q14416 1/20 0.39
RORC P51449 1/20 0.38
HCRTR2 O43614 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4445550 0.85 MAOB (0.47) MAOBMAOALMNAPTGS1CALML3
SCHEMBL4453979 0.83 MAOB (0.62) MAOBMAOALMNAPTGS1CALML3
SCHEMBL4168181 0.77 MAOA (0.55) MAOBMAOALMNAPTGS1CALML3
SCHEMBL4168179 0.77 MAOA (0.55) MAOBMAOALMNAPTGS1CALML3
SCHEMBL2406825 0.77 MAOB (0.67) MAOBMAOALMNAPTGS1CALML3
SCHEMBL2591003 0.77 MAOB (0.67) MAOBMAOALMNAPTGS1CALML3
SCHEMBL2406832 0.77 MAOB (0.67) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6854026 0.76 MAOA (0.53) MAOBMAOALMNAPTGS1CALML3
SCHEMBL4453975 0.76 F10 (0.42) MAOBMAOALMNAPTGS1CALML3
SCHEMBL4444205 0.75 MAOB (0.73) MAOBMAOALMNAPTGS1CALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1912980-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION Wockhardt Limited (IN) 2008-04-23 EP disclosed
WO-2007023507-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION WOCKHARDT LIMITED (IN) 2007-03-01 WO disclosed