SCHEMBL4862672

SCHEMBL4862672

Cc1ccccc1NC(=Nc1ccccc1)Nc1ccccc1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.55
POLB P06746 1/20 0.55
RAB9A P51151 2/20 0.52
NPC1 O15118 1/20 0.52
SIGMAR1 Q99720 4/20 0.51
CRHR1 P34998 1/20 0.51
GRIN2D O15399 2/20 0.50
GRIN3B O60391 2/20 0.50
GRIN1 Q05586 2/20 0.50
GRIN2A Q12879 2/20 0.50
GRIN2B Q13224 2/20 0.50
GRIN2C Q14957 2/20 0.50
GRIN3A Q8TCU5 2/20 0.50
ALDH1A1 P00352 1/20 0.50
MEN1 O00255 1/20 0.50
PABPC1 P11940 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
KMT2A Q03164 1/20 0.50
EBP Q15125 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6157830 0.81 SIGMAR1 (0.70) POLBSIGMAR1CRHR1GRIN2DGRIN3B
SCHEMBL11141010 0.81 SIGMAR1 (0.71) HPGDPOLBRAB9ANPC1SIGMAR1
SCHEMBL9819817 0.78 NPC1 (0.57) HPGDPOLBRAB9ANPC1SIGMAR1
SCHEMBL11185068 0.74 KMT2A (0.45) POLBRAB9ANPC1SIGMAR1CRHR1
SCHEMBL2740849 0.73 NPC1 (0.55) HPGDRAB9ANPC1SIGMAR1GRIN2D
SCHEMBL9806718 0.73 SIGMAR1 (0.65) HPGDPOLBRAB9ANPC1SIGMAR1
SCHEMBL9806717 0.73 SIGMAR1 (0.65) HPGDPOLBRAB9ANPC1SIGMAR1
SCHEMBL28659146 0.73 NPC1 (0.52) HPGDPOLBRAB9ANPC1SIGMAR1
SCHEMBL9819819 0.73 SIGMAR1 (0.65) HPGDPOLBRAB9ANPC1SIGMAR1
SCHEMBL78799 0.73 KMT2A (0.63) RAB9ANPC1SIGMAR1CRHR1GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9121776-B2 Welding arc apparel with UV or thermochromic activated images LINCOLN GLOBAL, INC. (US) 2015-09-01 US disclosed
US-9121776-B2 Welding arc apparel with UV or thermochromic activated images LINCOLN GLOBAL, INC. (US) 2015-09-01 US disclosed
US-9121776-B2 Welding arc apparel with UV or thermochromic activated images LINCOLN GLOBAL, INC. (US) 2015-09-01 US disclosed
WO-2014053907-A2 WELDING ARC APPAREL WITH UV OR THERMOCHROMIC ACTIVATED IMAGES LINCOLN GLOBAL, INC. (US) 2014-04-10 WO disclosed
WO-2014020386-A1 WELDING ACCESSORY WITH UV OR THERMOCHROMIC ACTIVATED IMAGES; SYSTEM FORAND METHOD OF DETECTING A THRESHOLD TEMPERATURE OF THERMAL RADIATION EXPOSURE DURING WELDING OPERATIONS LINCOLN GLOBAL, INC. (US) 2014-02-06 WO disclosed
US-20130026150-A1 WELDING ARC APPAREL WITH UV OR THEMOCHROMIC ACTIVATED IMAGES LINCOLN GLOBAL, INC. (US) 2013-01-31 US disclosed
US-20130026150-A1 WELDING ARC APPAREL WITH UV OR THEMOCHROMIC ACTIVATED IMAGES LINCOLN GLOBAL, INC. (US) 2013-01-31 US disclosed
US-20130026150-A1 WELDING ARC APPAREL WITH UV OR THEMOCHROMIC ACTIVATED IMAGES LINCOLN GLOBAL, INC. (US) 2013-01-31 US disclosed
US-7462443-B2 Leuco dye-containing coating compositions HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2008-12-09 US disclosed
US-7462443-B2 Leuco dye-containing coating compositions HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2008-12-09 US disclosed
US-7462443-B2 Leuco dye-containing coating compositions HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2008-12-09 US disclosed
WO-2005026274-A1 COATING COMPOSITIONS CONTAINING A LEUCO DYE-AND A DIARYLGUANIDINE DYE HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2005-03-24 WO disclosed
US-20050053870-A1 Leuco dye-containing coating compositions HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2005-03-10 US disclosed