Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 11/20 | 0.63 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486332 | 0.89 | F2R (0.64) | F2RLIPEMCHR1RORCPROKR1 | |
| SCHEMBL1581262 | 0.89 | F2R (0.51) | F2R | |
| SCHEMBL1581579 | 0.86 | F2R (0.61) | F2RMCHR1 | |
| SCHEMBL1580561 | 0.85 | F2R (0.60) | F2RLIPERORC | |
| SCHEMBL640711 | 0.85 | F2R (0.69) | F2RLIPERORCPROKR1KDM4E | |
| SCHEMBL1581286 | 0.84 | F2R (0.46) | F2R | |
| SCHEMBL1581804 | 0.82 | F2R (0.54) | F2R | |
| SCHEMBL3802875 | 0.81 | F2R (0.68) | F2RLIPEMCHR1RORCPROKR1 | |
| Hydrochloric Acid SCHEMBL661193 | 0.80 | F2R (0.67) | F2RLIPEMCHR1RORCPROKR1 | |
| SCHEMBL486495 | 0.80 | F2R (0.69) | F2RLIPERORCGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411363-B1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER IP GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108608-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-30 | — | — | WO | disclosed |