Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 11/20 | 0.64 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486268 | 0.89 | F2R (0.63) | F2RRORCLIPEMCHR1PROKR1 | |
| SCHEMBL1580804 | 0.89 | F2R (0.63) | F2RRORCLIPEEPHX2MCHR1 | |
| SCHEMBL3161600 | 0.89 | F2R (0.51) | F2REPHX2 | |
| SCHEMBL486495 | 0.85 | F2R (0.69) | F2RRORCLIPEUSP30 | |
| SCHEMBL3802720 | 0.85 | F2R (0.48) | F2RRORCLIPEKCNH2MCHR1 | |
| SCHEMBL485916 | 0.85 | F2R (0.63) | F2RRORCEPHX2 | |
| SCHEMBL1580501 | 0.84 | F2R (0.52) | F2RLIPEKCNH2PROKR1 | |
| SCHEMBL1580496 | 0.84 | F2R (0.58) | F2RKCNH2 | |
| SCHEMBL3800392 | 0.84 | F2R (0.64) | F2RLIPEKCNH2PROKR1 | |
| SCHEMBL3802875 | 0.83 | F2R (0.68) | F2RRORCLIPEMCHR1PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411363-B1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER IP GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108608-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-30 | — | — | WO | disclosed |