Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909127 | 0.86 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Methyl Ester SCHEMBL4861969 | 0.83 | TSHR (0.35) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid SCHEMBL4814346 | 0.81 | LMNA (0.42) | TSHRALDH1A1HSD17B10OR51E2LMNA | |
| Acrylic Acid Ethyl Ester SCHEMBL28810900 | 0.79 | TSHR (0.53) | TSHRHPGDHCAR2THRBALDH1A1 | |
| E968 SCHEMBL27988561 | 0.79 | TSHR (0.48) | TSHRHPGDHCAR2THRBALDH1A1 | |
| Acrylic Acid Ethyl Ester SCHEMBL5916258 | 0.79 | TSHR (0.48) | TSHRHPGDHCAR2THRBALDH1A1 | |
| Acrylic Acid Ethyl Ester SCHEMBL2703768 | 0.78 | TSHR (0.54) | TSHRHPGDHCAR2THRBALDH1A1 | |
| Acrylic Acid Ethyl Ester SCHEMBL28032335 | 0.78 | TSHR (0.48) | TSHRHPGDHCAR2THRBALDH1A1 | |
| Acrylic Acid Ethyl Ester SCHEMBL28460073 | 0.77 | TSHR (0.52) | TSHRHPGDHCAR2THRBALDH1A1 | |
| Acrylic Acid Ethyl Ester SCHEMBL27628563 | 0.77 | TSHR (0.52) | TSHRHPGDHCAR2THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130853-A1 | HYDRAZIDES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS - 681 | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | claimed |
| US-7416867-B2 | Enzymatic production of (meth)acrylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-26 | — | — | US | disclosed |
| US-20060141593-A1 | Enzymatic production of (meth) acrylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-29 | — | — | US | disclosed |