SCHEMBL4862797

SCHEMBL4862797

CC(=O)C(C(=O)O)C(C(C)=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.43
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
TP53 P04637 1/20 0.41
LMNA P02545 3/20 0.36
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.35
RECQL P46063 1/20 0.35
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
ABCB11 O95342 1/20 0.33
F2 P00734 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 1/20 0.33
BRD4 O60885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9761260 0.96 FFAR3 (0.40) FFAR3LCKFYNTP53LMNA
SCHEMBL380444 0.83 TP53 (0.42) FFAR3LCKFYNTP53ALDH1A1
SCHEMBL5268721 0.81 TP53 (0.40) FFAR3LCKFYNTP53ALDH1A1
SCHEMBL11280605 0.81 TP53 (0.40) FFAR3LCKFYNTP53ALDH1A1
SCHEMBL28073941 0.81 TP53 (0.40) FFAR3LCKFYNTP53ALDH1A1
SCHEMBL10481616 0.81 TP53 (0.47) FFAR3LCKFYNTP53ALDH1A1
SCHEMBL28961334 0.81 TP53 (0.40) FFAR3LCKFYNTP53ALDH1A1
SCHEMBL16937251 0.81 TP53 (0.33) FFAR3LCKFYNTP53MAPT
SCHEMBL28473671 0.81 TP53 (0.40) FFAR3LCKFYNTP53ALDH1A1
SCHEMBL3139061 0.81 LMNA (0.42) FFAR3LCKFYNTP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2008528252-A 2008-07-31 JP claimed
EP-1838438-A1 HYDROPROCESSING CATALYST, PREPARATION METHOD THEREOF AND USE OF SAME Total France (FR) 2007-10-03 EP claimed
WO-2006077326-A1 HYDROPROCESSING CATALYST, PREPARATION METHOD THEREOF AND USE OF SAME TOTAL FRANCE (FR) 2006-07-27 WO claimed
EP-1838438-B1 HYDROPROCESSING CATALYST, PREPARATION METHOD THEREOF AND USE OF SAME TOTAL RAFFINAGE FRANCE (FR) 2014-12-10 EP disclosed
EP-1838438-A1 HYDROPROCESSING CATALYST, PREPARATION METHOD THEREOF AND USE OF SAME Total France (FR) 2007-10-03 EP disclosed
WO-2006077326-A1 HYDROPROCESSING CATALYST, PREPARATION METHOD THEREOF AND USE OF SAME TOTAL FRANCE (FR) 2006-07-27 WO disclosed
EP-0641305-B1 THERMOSETTING COATING COMPOSITIONS EASTMAN CHEM CO (US) 1997-01-15 EP disclosed
EP-0641305-A1 THERMOSETTING COATING COMPOSITIONS. EASTMAN CHEM CO (US) 1995-03-08 EP disclosed
US-5359125-A Using 2,2'-bisacetoacetate as crosslinking agent EASTMAN CHEMICAL COMPANY (US) 1994-10-25 US disclosed
US-5359125-A Using 2,2'-bisacetoacetate as crosslinking agent EASTMAN CHEMICAL COMPANY (US) 1994-10-25 US disclosed
US-5254637-A Curable enamel with 2,2*-bisacetoacetate crosslinking agents EASTMAN KODAK COMPANY (US) 1993-10-19 US disclosed
US-5254637-A Curable enamel with 2,2*-bisacetoacetate crosslinking agents EASTMAN KODAK COMPANY (US) 1993-10-19 US disclosed
US-5247122-A 2,2'-bisacetoacetates useful as crosslinking agents EASTMAN KODAK COMPANY (US) 1993-09-21 US disclosed
US-5247122-A 2,2'-bisacetoacetates useful as crosslinking agents EASTMAN KODAK COMPANY (US) 1993-09-21 US disclosed
WO-1992021646-A1 THERMOSETTING COATING COMPOSITIONS EASTMAN KODAK COMPANY (US) 1992-12-10 WO disclosed