Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512532 | 0.78 | TSHR (0.48) | CALM1CES2CES1TSHRALDH1A1 | |
| Iodide SCHEMBL7700643 | 0.76 | TSHR (0.46) | CALM1CES2CES1TSHRALDH1A1 | |
| SCHEMBL8726910 | 0.75 | TAAR1 (0.39) | IDO1TAAR1CYP2A6HTR2ASMN1; SMN2 | |
| SCHEMBL6045125 | 0.75 | CYP3A4 (0.38) | IDO1CYP1A2 | |
| SCHEMBL7903067 | 0.74 | TP53 (0.43) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| SCHEMBL14306650 | 0.74 | TSHR (0.43) | CALM1CES2CES1TSHRALDH1A1 | |
| SCHEMBL73253 | 0.74 | CPA1 (0.47) | CALM1CES2CES1ALDH1A1CYP1A2 | |
| SCHEMBL27673225 | 0.74 | CPA1 (0.47) | CALM1CES2CES1ALDH1A1CYP1A2 | |
| SCHEMBL6045093 | 0.73 | IDO1 (0.46) | TSHRIDO1MAOBSIGMAR1CYP1A2 | |
| SCHEMBL31211948 | 0.72 | CPA1 (0.46) | CALM1CES2CES1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292446-B | Method for preparing N-benzylhydroxylamine hydrochloride with high yield | 广州康瑞泰药业有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-113292446-A | Method for preparing N-benzylhydroxylamine hydrochloride with high yield | 广州康瑞泰药业有限公司 | 2021-08-24 | — | — | CN | claimed |
| EP-0366560-A1 | Tylosin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1990-05-02 | — | — | EP | claimed |
| CN-120647596-A | Trifluoromethyl isoxazolidine-containing compound and synthetic method and pharmaceutical application thereof | 河南师范大学 | 2025-09-16 | — | — | CN | disclosed |
| US-20240239771-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | TAXIS PHARMACEUTICALS, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240239771-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | TAXIS PHARMACEUTICALS, INC. | 2024-07-18 | — | — | US | disclosed |
| CN-116239492-B | Continuous synthesis process of N-benzyl hydroxylamine hydrochloride | 中南大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-116239492-A | Continuous synthesis process of N-benzyl hydroxylamine hydrochloride | 湖南华纳大药厂科技开发有限公司 | 2023-06-09 | — | — | CN | disclosed |
| EP-3863632-B1 | QUINOLYLNITRONE FOR USE IN THE TREATMENT AND PREVENTION OF A CEREBRAL STROKE OR ISCHAEMIA | ISQUAEMIA BIOTECH S L (ES) | 2023-06-07 | — | — | EP | disclosed |
| CN-113292446-B | Method for preparing N-benzylhydroxylamine hydrochloride with high yield | 广州康瑞泰药业有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-114292207-A | Production process of N-benzylhydroxylamine hydrochloride | 苏州诚和医药化学有限公司 | 2022-04-08 | — | — | CN | disclosed |
| WO-2000006525-A9 | SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS | HARVARD COLLEGE (US) | 2000-04-20 | — | — | WO | disclosed |
| WO-2000006525-A2 | SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-02-10 | — | — | WO | disclosed |
| US-5998627-A | Preparation and uses of hydrocarbylnitrones | ALBEMARLE CORPORATION (US) | 1999-12-07 | — | — | US | disclosed |
| WO-1999006362-A1 | PREPARATION AND USES OF HYDROCARBYLNITRONES | ALBEMARLE CORPORATION (US) | 1999-02-11 | — | — | WO | disclosed |
| US-5122610-A | Renin inhibitor intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-16 | — | — | US | disclosed |
| EP-0366560-A1 | Tylosin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1990-05-02 | — | — | EP | disclosed |
| US-4080340-A | Nitroimidazoles | MERCK & CO., INC. (US) | 1978-03-21 | — | — | US | disclosed |
| US-4010176-A | Isoxazole substituted nitroimidazoles | MERCK & CO., INC. (US) | 1977-03-01 | — | — | US | disclosed |
| US-4006225-A | Method of using reduction products of everninomicins as antibacterial agents and pharmaceutical compositions useful therefor | SCHERING CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239771-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | ABCB11, ABCB1, SLC47A1 | CALM1 3712/4885CES2 543/4885CES1 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.