Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308389 | 0.98 | LMNA (0.48) | LMNATDP1L3MBTL1PDE4AUSP2 | |
| SCHEMBL11210752 | 0.95 | LMNA (0.48) | LMNATDP1L3MBTL1PDE4AUSP2 | |
| Potassium Ion SCHEMBL9419061 | 0.95 | LMNA (0.48) | LMNATDP1L3MBTL1PDE4AUSP2 | |
| SCHEMBL15007775 | 0.95 | LMNA (0.48) | LMNATDP1L3MBTL1PDE4AUSP2 | |
| SCHEMBL4734230 | 0.95 | LMNA (0.53) | LMNATDP1L3MBTL1PDE4AUSP2 | |
| SCHEMBL10356239 | 0.95 | LMNA (0.48) | LMNATDP1L3MBTL1PDE4AUSP2 | |
| SCHEMBL3899113 | 0.95 | LMNA (0.48) | LMNATDP1L3MBTL1PDE4AUSP2 | |
| SCHEMBL11033302 | 0.95 | LMNA (0.48) | LMNATDP1L3MBTL1PDE4AUSP2 | |
| SCHEMBL3862937 | 0.95 | LMNA (0.48) | LMNATDP1L3MBTL1PDE4AUSP2 | |
| SCHEMBL5559507 | 0.95 | LMNA (0.48) | LMNATDP1L3MBTL1PDE4AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776436-B1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL INC (US) | 2019-05-08 | — | — | EP | disclosed |
| US-7465415-B2 | Photochromic materials derived from ring-opening monomers and photochromic initiators | PPG INDUSTRIES OHIO, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| EP-1776436-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006022825-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060022176-A1 | Reaction product of a ring-opening cyclic ester or carbonate and a photochromic initiator, especially a naphtho[1,2-b]quinone with one or more hydroxy groups, e.g., (1) 3,3-di(4-methoxyphenyl)-6,7-dimethoxy-13-methyl-13-(2-(2-hydroxyethoxy)ethoxy)-3H,13H-indeno[2,1-f]naphtho[1,2-b]pyran. | TRANSITIONS OPTICAL LIMITED (IE) | 2006-02-02 | — | — | US | disclosed |