Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 14/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485857 | 0.84 | F2R (0.64) | F2RCYP2C19RAB9A | |
| SCHEMBL10242070 | 0.81 | F2R (0.86) | F2RHPGDCYP2C19 | |
| Hydrochloric Acid SCHEMBL485864 | 0.81 | F2R (0.84) | F2RHPGDCYP2C19 | |
| SCHEMBL485923 | 0.79 | F2R (0.73) | F2RCYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL661951 | 0.78 | F2R (0.70) | F2RHPGDMAPTHTTRAB9A | |
| SCHEMBL10241116 | 0.76 | F2R (1.00) | F2RHPGDLMNAMAPTHTT | |
| SCHEMBL10242029 | 0.75 | F2R (0.62) | F2RHPGD | |
| Hydrochloric Acid SCHEMBL661995 | 0.75 | F2R (0.98) | F2RHPGDLMNAMAPTHTT | |
| SCHEMBL10242030 | 0.70 | F2R (0.69) | F2RHPGD | |
| SCHEMBL486325 | 0.69 | F2R (0.68) | F2RHPGDNPSR1CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108608-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-30 | — | — | WO | disclosed |