Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RHOA | P61586 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4863291 | 0.79 | CYP3A4 (0.51) | CYP3A4ALDH1A1HSD17B10TSHRRHOA | |
| SCHEMBL17386427 | 0.74 | CYP3A4 (0.76) | CYP3A4ALDH1A1HSD17B10TSHRRHOA | |
| SCHEMBL11799224 | 0.74 | CYP3A4 (0.65) | CYP3A4ALDH1A1HSD17B10TSHRRHOA | |
| SCHEMBL4787535 | 0.72 | CYP3A4 (0.47) | CYP3A4ALDH1A1HSD17B10TSHRRHOA | |
| SCHEMBL16371573 | 0.71 | CYP3A4 (1.00) | CYP3A4ALDH1A1HSD17B10TSHRRHOA | |
| SCHEMBL15174 | 0.71 | CYP3A4 (1.00) | CYP3A4ALDH1A1HSD17B10TSHRRHOA | |
| SCHEMBL29362146 | 0.71 | CYP3A4 (1.00) | CYP3A4ALDH1A1HSD17B10TSHRRHOA | |
| SCHEMBL27474785 | 0.71 | CYP3A4 (1.00) | CYP3A4ALDH1A1HSD17B10TSHRRHOA | |
| SCHEMBL960227 | 0.70 | CYP3A4 (0.76) | CYP3A4ALDH1A1HSD17B10TSHRRHOA | |
| SCHEMBL15485816 | 0.70 | CYP3A4 (0.74) | CYP3A4ALDH1A1HSD17B10TSHRRHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972624-A1 | Benzoxazinones and their use as ultraviolet light absorbers | Clariant International Ltd. (CH) | 2008-09-24 | — | — | EP | disclosed |