Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633547 | 0.81 | ALDH1A1 (0.63) | MAOBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL4863286 | 0.79 | CYP3A4 (0.54) | CYP3A4KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL9660322 | 0.78 | NMT1 (0.57) | MAOBKDM4EALDH1A1TSHRMAPT | |
| SCHEMBL4787535 | 0.76 | CYP3A4 (0.47) | CYP3A4KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL6688219 | 0.76 | ALDH1A1 (0.51) | CYP3A4KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL3205728 | 0.76 | KDM4E (0.42) | CYP3A4MAOBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4651653 | 0.75 | MAPK1 (0.71) | MAOBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL31347574 | 0.75 | MAPK1 (0.71) | MAOBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL31232901 | 0.73 | ALDH1A1 (0.41) | CYP3A4KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL11799224 | 0.72 | CYP3A4 (0.65) | CYP3A4KDM4EALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972624-A1 | Benzoxazinones and their use as ultraviolet light absorbers | Clariant International Ltd. (CH) | 2008-09-24 | — | — | EP | disclosed |
| US-3976780-A | Methods of protection against emesis in mammals by administration of a 3-alkoxy-thianaphthene-2-carboxamide | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES L'ILE-DE-FRANCE (FR) | 1976-08-24 | — | — | US | disclosed |
| US-3954748-A | ANTIEMETICS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1976-05-04 | — | — | US | disclosed |