Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL6245904 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BSLC34A1 | |
| Phosphoric Acid SCHEMBL10423194 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BSLC34A1 | |
| Phosphoric Acid SCHEMBL9001553 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BSLC34A1 | |
| Phosphoric Acid SCHEMBL11873198 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BSLC34A1 | |
| Phosphoric Acid SCHEMBL22436350 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BSLC34A1 | |
| Phosphoric Acid SCHEMBL9001559 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BSLC34A1 | |
| Phosphoric Acid SCHEMBL9227688 | 0.92 | KMT2A (0.46) | MEN1KMT2ACA5ACA5BSLC34A1 | |
| Phosphoric Acid SCHEMBL1071852 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BSLC34A1 | |
| Phosphoric Acid SCHEMBL11553763 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BSLC34A1 | |
| Phosphoric Acid SCHEMBL11873193 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BSLC34A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7341664-B2 | Method for forming an in situ groundwater filter | AUBURN UNIVERSITY (US) | 2008-03-11 | — | — | US | disclosed |
| US-20040222151-A1 | Method and system for forming an in situ groundwater filter | ENVIROTRACE, LLC | 2004-11-11 | — | — | US | disclosed |
| WO-2003053865-A1 | METHOD AND SYSTEM FOR FORMING AN IN SITU GROUNDWATER FILTER | AUBURN UNIVERSITY (US) | 2003-07-03 | — | — | WO | disclosed |
| US-20030037924-A1 | Remediation method | ELLIS MARK T (US) | 2003-02-27 | — | — | US | disclosed |
| US-6464005-B1 | Remediation method | ELLIS MARK T (US) | 2002-10-15 | — | — | US | disclosed |