Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | S100B | P04271 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | IL1B | P01584 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3856746 | 0.86 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL3857353 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL3867323 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL11466571 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL4859720 | 0.77 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL5127559 | 0.76 | RXRB (0.44) | ALDH1A1TDP1POLBNPSR1NPC1 | |
| SCHEMBL5122978 | 0.76 | ABCG2 (0.39) | ALDH1A1TSHRARPOLBNPSR1 | |
| SCHEMBL22964522 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TDP1RECQLPOLB | |
| SCHEMBL29446083 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TDP1RECQLPOLB | |
| SCHEMBL12311916 | 0.73 | GRM4 (0.42) | ALDH1A1CYP3A4TDP1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | claimed |
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | claimed |
| EP-1568355-A1 | N-alkylhydroxilated secondary paraphenylenediamine which is ortho- and/or meta substituted, composition for dying keratinous fibres comprising this paraphenylenediamine, methods based on this composition and uses. | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | disclosed |
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | disclosed |
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | disclosed |
| US-20080058383-A1 | Androgen Receptor Modulators | KARO BIO AB (SE) | 2008-03-06 | — | — | US | disclosed |
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | KRT18, CDC73, TYR | ALDH1A1 968/4885CYP3A4 854/4885TDP1 1822/4885 |
| US-20080058383-A1 | Androgen Receptor Modulators | NR5A1, ESRRA, AR | ALDH1A1 567/4885CYP3A4 1601/4885TDP1 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.