SCHEMBL486383

SCHEMBL486383

CCCCc1cccc(C(N)=O)c1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
NR1I2 O75469 1/20 0.45
LMNA P02545 1/20 0.45
CHRM2 P08172 1/20 0.45
CYP3A4 P08684 1/20 0.45
ADRA2A P08913 1/20 0.45
MAPT P10636 1/20 0.45
OPRK1 P41145 1/20 0.45
HTR2B P41595 1/20 0.45
SLC6A3 Q01959 1/20 0.45
KMT2A Q03164 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
KAT8 Q9H7Z6 2/20 0.42
PPARA Q07869 2/20 0.42
PPARG P37231 1/20 0.42
EP300 Q09472 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6013407 0.95 BID (0.48) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL7517986 0.94 BID (0.50) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL6013409 0.94 BID (0.50) MEN1NR1I2LMNACHRM2CYP3A4
Hydrochloric Acid SCHEMBL7557316 0.92 BID (0.49) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL461600 0.90 PARP1 (0.41) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL30514834 0.87 PARP1 (0.38) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL6285466 0.87 CYP3A4 (0.45) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL28182515 0.87 PARP1 (0.38) MEN1NR1I2LMNACHRM2CYP3A4
Charcoal, Activated SCHEMBL9345982 0.85 CYP3A4 (0.44) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL28298922 0.85 MEN1 (0.38) MEN1NR1I2LMNACHRM2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112521560-A Efficient salt-resistant one-agent dual-purpose thickening agent and preparation method and application thereof 西安长庆化工集团有限公司 2021-03-19 CN claimed
CN-112521560-B Efficient salt-resistant one-dose dual-purpose thickening agent and preparation method and application thereof 西安长庆化工集团有限公司 2023-05-30 CN disclosed
CN-112521560-A Efficient salt-resistant one-agent dual-purpose thickening agent and preparation method and application thereof 西安长庆化工集团有限公司 2021-03-19 CN disclosed
EP-2411384-A1 INSECTICIDAL COMPOUNDS Syngenta Participations AG (CH) 2012-02-01 EP disclosed
WO-2010108733-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2010-09-30 WO disclosed