Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.48 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013409 | 0.98 | BID (0.50) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL7517986 | 0.98 | BID (0.50) | BIDMCL1PPARABCL2L1BAK1 | |
| Hydrochloric Acid SCHEMBL7557316 | 0.97 | BID (0.49) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL486383 | 0.95 | MEN1 (0.45) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL461600 | 0.88 | PARP1 (0.41) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL22736732 | 0.87 | BID (0.48) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL28297464 | 0.86 | MEN1 (0.38) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL28850518 | 0.86 | BID (0.50) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL28186455 | 0.86 | BID (0.50) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL9342125 | 0.85 | BID (0.56) | BIDMCL1PPARABCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7126027-B2 | N-[(1-dimethylaminocycloalkyl)methyl]benzamide derivatives | AKZO NOBEL N.V. (NL) | 2006-10-24 | — | — | US | disclosed |