SCHEMBL4864336

SCHEMBL4864336

CO[Sn](OC)(OC)c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
CYP2A6 P11509 4/20 0.43
MAPT P10636 1/20 0.41
TSHR P16473 3/20 0.40
HSD17B10 Q99714 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP1A2 P05177 4/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
KEAP1 Q14145 1/20 0.38
HPRT1 P00492 1/20 0.37
RAB9A P51151 1/20 0.37
F2 P00734 1/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
SLC6A4 P31645 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4864301 0.78 HPGD (0.40) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL5952012 0.75 ALDH1A1 (0.48) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL11805218 0.70 ALDH1A1 (0.46) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL10916663 0.70 CYP1A2 (0.48) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL15529474 0.70 ALDH1A1 (0.46) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL11761232 0.70 CYP1A2 (0.48) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL8056327 0.70 CYP1A2 (0.48) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL8052201 0.70 ALDH1A1 (0.46) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL8056313 0.70 ALDH1A1 (0.46) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL1029428 0.68 ALDH1A1 (0.43) ALDH1A1CYP2A6TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7393560-B2 Organo-metal compounds BRAGGONE OY (FI) 2008-07-01 US claimed
US-20060263621-A1 Novel organo-metal compounds BRAGGONE OY (FI) 2006-11-23 US claimed
US-7393560-B2 Organo-metal compounds BRAGGONE OY (FI) 2008-07-01 US disclosed
US-20060263621-A1 Novel organo-metal compounds BRAGGONE OY (FI) 2006-11-23 US disclosed