Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ACP1 | P24666 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4835671 | 0.92 | RAB9A (0.42) | RAB9AMAPTNPC1LMNAKDM4E | |
| SCHEMBL4839792 | 0.85 | RAB9A (0.56) | RAB9AMAPTNPC1LMNAKDM4E | |
| SCHEMBL4842797 | 0.84 | RAB9A (0.39) | RAB9AMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL4835901 | 0.83 | RAB9A (0.42) | RAB9AMAPTNPC1LMNAKDM4E | |
| SCHEMBL4835055 | 0.83 | RAB9A (0.49) | RAB9AMAPTNPC1KDM4EHSD17B10 | |
| SCHEMBL4839938 | 0.83 | ABL1 (0.47) | RAB9AMAPTNPC1KDM4EHSD17B10 | |
| SCHEMBL21525047 | 0.81 | RAB9A (0.38) | RAB9AMAPTLMNAALDH1A1MAPK10 | |
| SCHEMBL21525045 | 0.80 | RAB9A (0.37) | RAB9AACP1PTPN7PTPN12PTPN13 | |
| SCHEMBL4844727 | 0.78 | MEN1 (0.39) | RAB9AMAPTNPC1LMNAKDM4E | |
| SCHEMBL4844713 | 0.78 | RAB9A (0.45) | RAB9AMAPTNPC1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7411065-B2 | Peptide nucleic acid monomers: diphenylmethyl, benzyl, alkylthioalkyl, or phenylthioalkyl esters of N-(1-[4-(2-benzothiazolyl-, 2-benzoxazolyl-, 2-benzofuranyl- or 2-benzothiophenyl-sulfonyl)-3-piperazinon-1-ylcarbonylmethyl]pyrimidon-4-yl)carbamic acids | PANAGENE, INC. (KR) | 2008-08-12 | — | — | US | disclosed |