Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864333 | 0.86 | TNF (0.36) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL9416048 | 0.85 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL9846541 | 0.81 | KDM4E (0.36) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9846461 | 0.81 | KDM4E (0.36) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9846543 | 0.80 | KDM4E (0.36) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9846570 | 0.80 | KDM4E (0.36) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9846578 | 0.80 | KDM4E (0.36) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2226707 | 0.78 | KDM4E (0.57) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL5945948 | 0.77 | KDM4E (0.58) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7615094 | 0.77 | KDM4E (0.57) | KCNH2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089388-B1 | PROCESS FOR THE SYNTHESIS OF MOXIFLOXACIN HYDROCHLORIDE | CIPLA LTD (IN) | 2014-01-29 | — | — | EP | claimed |
| US-7365201-B2 | Process for the preparation of the boron difluoride chelate of quinolone-3-carboxylic acid | APOTEX PHARMACHEM INC. | 2008-04-29 | — | — | US | claimed |
| US-20070208174-A1 | Process for the preparation of the boron difluoride chelate of quinolone-3-carboxylic acid | APOTEX PHARMACHEM INC. | 2007-09-06 | — | — | US | claimed |
| WO-2004101527-A1 | PROCESS FOR PREPARING OMEGA-ANHYDROUS GATIFLOXACIN | CADILA HEALTHCARE LIMITED (IN) | 2004-11-25 | — | — | WO | claimed |
| US-7365201-B2 | Process for the preparation of the boron difluoride chelate of quinolone-3-carboxylic acid | APOTEX PHARMACHEM INC. | 2008-04-29 | — | — | US | disclosed |
| US-7365201-B2 | Process for the preparation of the boron difluoride chelate of quinolone-3-carboxylic acid | APOTEX PHARMACHEM INC. | 2008-04-29 | — | — | US | disclosed |
| US-20070208174-A1 | Process for the preparation of the boron difluoride chelate of quinolone-3-carboxylic acid | APOTEX PHARMACHEM INC. | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208174-A1 | Process for the preparation of the boron difluoride chelate of quinolone-3-carboxylic acid | ABL1, SFXN3, CA6 | KCNH2 61/4885KDM4E 2027/4885ALDH1A1 3490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.