Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564385 | 0.88 | KDM4E (0.42) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL14153907 | 0.87 | MAPT (0.41) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL28420950 | 0.85 | MIF (0.46) | MAPTNPC1RAB9APOLBCTSL | |
| SCHEMBL14108128 | 0.85 | EPHX2 (0.41) | MAPTSMN1; SMN2TP53POLBKMT2A | |
| SCHEMBL10565579 | 0.83 | AKT1 (0.49) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL1780463 | 0.82 | MAPT (0.43) | MAPTNPC1RAB9ASMN1; SMN2NOX1 | |
| SCHEMBL10566349 | 0.81 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2CYP1A2POLB | |
| SCHEMBL10565261 | 0.81 | NOX1 (0.46) | MAPTNPC1RAB9ASMN1; SMN2NOX1 | |
| SCHEMBL1781292 | 0.81 | NPC1 (0.46) | MAPTNPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL4083109 | 0.80 | KDM4E (0.37) | MAPTNPC1RAB9ACYP1A2CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405280-B2 | Chromogenic substances and use thereof for the determination of carboxypeptidase activities | DIAGNOSTICA STAGO (FR) | 2008-07-29 | — | — | US | disclosed |
| US-7405280-B2 | Chromogenic substances and use thereof for the determination of carboxypeptidase activities | DIAGNOSTICA STAGO (FR) | 2008-07-29 | — | — | US | disclosed |
| US-7405280-B2 | Chromogenic substances and use thereof for the determination of carboxypeptidase activities | DIAGNOSTICA STAGO (FR) | 2008-07-29 | — | — | US | disclosed |
| US-20050107305-A1 | Novel chromogenic substances and use thereof for the determination of carboxypeptidase activities | SOCIETE DIAGNOSTICA-STAGO (FR) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107305-A1 | Novel chromogenic substances and use thereof for the determination of carboxypeptidase activities | CPA3, CPA4, CPA1 | MAPT 4668/4885NPC1 2059/4885RAB9A 3754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.